Home Tools
Log in
Cart

Search Result

Search Results for " 5-ht4 agonist "

20

Compounds

Cat No. Product Name Synonyms Targets
T1291 Cisapride Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase Potassium Channel , 5-HT Receptor , HER
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease...
T22992 ML 10302 hydrochloride 5-HT Receptor
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3.
T21946 BIMU 8 5-HT Receptor
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
T22671 CJ 033466 5-HT Receptor
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.
T6958 Prucalopride Succinate R-108512,Resolor Succinate 5-HT Receptor
Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively.
T28934 Felcisetrag TD 8954,TD8954,TD-8954 5-HT Receptor
Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi o...
T38507 Renzapride BRL 24924 5-HT Receptor
Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-predominant irritable bowel syndrome (C-IBS).
T27117 DA-6886 DA6886,DA 6886 5-HT Receptor
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressin...
T68035 Capeserod SL-650155,SL-65.0155 5-HT Receptor
Capeserod is a potential 5-HT4 receptor (5-hydroxytryptamine receptor 4) agonist for the study of digestive disorders and neurological disorders.
T5336 Zacopride hydrochloride Potassium Channel , 5-HT Receptor
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
T28043L Minesapride 5-HT Receptor
Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation.
T68116L (Rac)-Norcisapride 5-HT Receptor
Norcisapride is a 5-hydroxytryptamine receptor 3 (5-HT3) and (5-hydroxytryptamine receptor 4 (5-HT4) dual agonist used for the treatment of gastrointestinal disorders, orofacial disorders, and otorhinolaryngologic disord...
T21385 Cinitapride Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove 5-HT Receptor
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag...
T23265 RS 67333 hydrochloride RS 67333 (hydrochloride),RS 67333 HCl 5-HT Receptor
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu...
T1551 Tegaserod maleate HTF-919,SDZ-HTF-919 5-HT Receptor
Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug ...
T4616 Metoclopramide 5-Chloro-2-methoxyprocainamide Dopamine Receptor , 5-HT Receptor
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ...
T23791 BIMU-1
BIMU-1 is an agonist of 5-HT4 receptor.
T28696 SC 53116 Hydrochloride SC 53116,SC53116,SC-53116,SC 53116 HCl
SC 53116 Hydrochloride is selective agonist of the newly identified serotonin 5-HT4 receptor subtype.
T2542L Prucalopride hydrochloride Prucalopride HCl
Prucalopride hydrochloride is a selective agonist of the 5-HT4.
T29115 VRX 03011 Potassium salt PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140
VRX 03011, a 5-HT4 partial agonist, is used potentially for the treatment of Alzheimer's disease.

Compounds

Cisapride
T1291
Synonym: Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase
Target: Potassium Channel, 5-HT Receptor, HER
ML 10302 hydrochloride
T22992
Synonym:
Target: 5-HT Receptor
BIMU 8
T21946
Synonym:
Target: 5-HT Receptor
CJ 033466
T22671
Synonym:
Target: 5-HT Receptor
Prucalopride Succinate
T6958
Synonym: R-108512,Resolor Succinate
Target: 5-HT Receptor
Felcisetrag
T28934
Synonym: TD 8954,TD8954,TD-8954
Target: 5-HT Receptor
Renzapride
T38507
Synonym: BRL 24924
Target: 5-HT Receptor
DA-6886
T27117
Synonym: DA6886,DA 6886
Target: 5-HT Receptor
Capeserod
T68035
Synonym: SL-650155,SL-65.0155
Target: 5-HT Receptor
Zacopride hydrochloride
T5336
Synonym:
Target: Potassium Channel, 5-HT Receptor
Minesapride
T28043L
Synonym:
Target: 5-HT Receptor
(Rac)-Norcisapride
T68116L
Synonym:
Target: 5-HT Receptor
Cinitapride
T21385
Synonym: Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove
Target: 5-HT Receptor
RS 67333 hydrochloride
T23265
Synonym: RS 67333 (hydrochloride),RS 67333 HCl
Target: 5-HT Receptor
Tegaserod maleate
T1551
Synonym: HTF-919,SDZ-HTF-919
Target: 5-HT Receptor
Metoclopramide
T4616
Synonym: 5-Chloro-2-methoxyprocainamide
Target: Dopamine Receptor, 5-HT Receptor
BIMU-1
T23791
Synonym:
Target:
SC 53116 Hydrochloride
T28696
Synonym: SC 53116,SC53116,SC-53116,SC 53116 HCl
Target:
Prucalopride hydrochloride
T2542L
Synonym: Prucalopride HCl
Target:
VRX 03011 Potassium salt
T29115
Synonym: PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140
Target:
1 2
TargetMol